For many couples, reliable birth control is an important aspect of their relationships. The field of male contraception is evolving to become more accessible and mainstream. Traditionally, a majority of birth control options are the responsibility of women. For male contraceptives to gain widespread acceptance, a broad shift in mindset is essential. Men must be encouraged and willing to take an active role in birth control.
A new clinical trial at UC Davis Health is now attempting to advance that conversation and expand the male contraceptive market with their development of a reversible hormonal birth control gel for men. This new innovation of hormonal gel comes in a convenient canister that contains a progestin called Nesterone. To use it simply apply it to the shoulders. The Nesterone prevents the testes from making sperm but also stops natural testosterone production. To combat the depletion, testosterone is added so as not to hinder any physical capabilities. The composition of the gel is similar to female hormonal birth control, which uses both progestin and estrogen in order to prevent pregnancy. The side effects are similar to female birth control as well and include hair growth or loss, decreased libido, and minor weight gain. One canister can hold two weeks’ doses. UC Davis researchers described their achievement as a comparable product to female birth control pills.
Another team of researchers at Weill Cornell Medicine is targeting the soluble adenylyl cyclase enzyme that promotes sperm motility, essentially hoping to immobilize sperm. Their study may produce another temporary form of safe contraceptive, but it is still in the early stages of clinical development.
The drawback is that male hormonal contraceptives are still lacking pharmaceutical investment and raise concerns about severe side effects. Furthermore, while men produce millions of sperm daily, women can produce one egg a month. This difference is where the focus shifts to female anatomy and responsibility. Releasing the hormonal gel to market may spark a much-needed discussion that can create social change.
Ultimately, the success of male birth control hinges not just on scientific progress but also on social progress. The aim of expanding the market to include male birth control products is to share the responsibility of contraception. Although fairly new, clinical trials show promising results, but the usability of new products is unapproachable as a common contraception. To become widespread there must be a shift in social stigma and perceptions on contraceptives and the topic of responsibility.
“Ultimately, the success of male birth control hinges not just on scientific progress but also on social progress.“
